Mar 1, 2026

2 min

The 90-Day Cellular Reset (and why you need it)

Fact checked by

The Rerise Health Science Team

Why Every Human Needs a Cellular Reset

When it comes to feeling energized and sharp, lasting results require commitment. True transformation comes from cellular change, and science reveals this kickstarts in approximately 90 days. Here’s your roadmap to a genuine cellular reset, supported by clinical evidence.

Ready to feel GREAT?

Days 1-7: Turning Your Cells Back On

In your first week, boosting nutrients such as NMN, CoQ10, and B vitamins starts to elevate NAD+ levels. NAD+ is critical to energy production, DNA repair, and mitochondrial health. Early studies indicate that supplementing these nutrients can lead to noticeable improvements in mental clarity and initial boosts in physical energy within one week [1].

Days 8-30: Amplifying Energy Production

During weeks two to four, mitochondrial biogenesis - creation of new mitochondria - increases significantly thanks to compounds like PQQ and PrimaVie® Shilajit [2]. Research shows that consistent use of these ingredients for three weeks significantly improves cognitive performance, reduces fatigue, and enhances exercise recovery [3,4].

Days 31-60: Sharpening Mental Clarity

Between weeks five and eight, ingredients such as Acetyl-L-Carnitine and CoQ10 phytosome deeply enhance neuronal function. Clinical trials have demonstrated significant gains in cognitive tests for participants supplementing these nutrients, including improved focus, memory recall, and reduced mental fatigue [5,6].

Days 61-90: Restoring Full Cellular Vitality

By days 60-90, you reach optimal mitochondrial efficiency. NAD+ pathways are fully engaged, and redox balance is significantly improved by powerful antioxidants like R-Lipoic Acid. Studies show these deeper cellular changes produce measurable long-term benefits such as sustained energy, cognitive resilience, lower inflammation, and improved biomarkers of aging [7,8].

Beyond Day 90: Maintaining Cellular Health

Your cellular reset establishes a new baseline. Continuing these cellular-optimizing nutrients ensures sustained health, preventing mitochondrial decline and protecting against long-term cognitive and metabolic disorders [9].

Remember benefits compound over time - the longer you stick with the program, the better you feel (for real).

Interested in your own personalized cellular reset plan? Boy do we have just the product for you (think: Core100). We designed the Core100 protocol as a 90-day reset, that continues onward helping you feel GREAT.

We’d love to discuss how we can optimize your health. Reach out directly at hello@rerisehealth.com.

References
[1] Yoshino, J., et al. (2018). NAD+ intermediates in mitochondrial function. Cell Metabolism. Link
[2] Harris, C. B., et al. (2013). PQQ and mitochondrial biogenesis. Adv Nutr. Link
[3] Das, A., et al. (2016). PrimaVie® Shilajit for energy and recovery. J Med Food. Link
[4] Nakano, M., et al. (2009). Cognitive enhancement from PQQ. J Nutr Sci Vitaminol. Link
[5] Montgomery, S. A., et al. (2003). Acetyl-L-Carnitine cognitive improvement. Int Clin Psychopharmacol. Link
[6] Littarru, G. P., & Tiano, L. (2010). CoQ10 benefits cognition. Nutrition. Link
[7] Shay, K. P., et al. (2009). R-Lipoic Acid and antioxidant effects. Biochim Biophys Acta. Link
[8] Covarrubias, A. J., et al. (2021). Long-term NAD+ elevation. Nat Rev Mol Cell Biol. Link
[9] Hood, D. A., et al. (2019). Maintenance of mitochondrial health. Annu Rev Physiol. Link

Written by

Conrad Ukropina