Why Core100?
A baseline your week can trust
Core100 supports mitochondrial output and the systems that keep energy and recovery steady.
Fatigue starts when NAD+ and mitochondria decline…
Core100 works on your cellular infrastructure.
Most stacks chase symptoms.
Core100 supports mitochondrial performance and the systems around it - so energy holds up longer, and recovery feels less fragile.
Mitochondrial support
Supports NAD+ salvage and renewal inside the cell
Steadier energy
Supports redox balance so mitochondria can produce energy with less wear
Repair + defense support
Supports antioxidant and repair pathways so recovery feels more reliable
Benefits
Benefits
Sharper mornings. Steadier afternoons.
Supports NAD+ pathways that drive efficient energy metabolism
Helps daily tiredness feel less constant
Supports NAD+ pathways that drive efficient energy metabolism
Helps daily tiredness feel less constant
Sustained Energy
38%
38%
NAD⁺ in 8 weeks
Recover fast, tackle challenges with ease
Activates antioxidant and autophagy pathways to help protect and repair cells
Helps speed recovery from stress, exertion, and busy days
Recovery
30–40%
30–40%
Faster recovery time
Cognition
Decreases biomarkers of inflammation (CRP, MDA) by 20–35% in clinical trials³
Improved cognition
Improved cognition
Within
12 weeks
Within 12 weeks
Baseline
After 12 weeks
Resilience
Increases cellular NAD⁺ by up to 38% in 8 weeks¹ for sustained daily energy.
Increases cellular NAD⁺ by up to 38% in 8 weeks¹ for sustained daily energy.
Healthy Aging
Improves memory, focus, and cognitive speed in adults aged 50+ in as little as 12 weeks⁴.
Improves memory, focus, and cognitive speed in adults aged 50+ in as little as 12 weeks⁴.
Built for high-output adults
When work, family, travel, and training run hot, Core100 helps your baseline hold.
A daily protocol engineered that reinforces stamina, clarity, and bounce-back.
Built for high-output adults
When work, family, travel, and training run hot, Core100 helps your baseline hold.
A daily protocol engineered that reinforces stamina, clarity, and bounce-back.
Benefits you'll feel
Benefits you'll feel
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Week
1
Smoother energy and focus as mitochondrial nutrients and B vitamins start refilling cellular pathways.
Week
8
Noticeable stamina and easier recovery as NMN, shilajit, CoQ10, and PQQ reach effective levels.
Week
16
Deeper resilience on long days as sustained NAD+ and mitochondrial support expand cellular energy reserves.
Week
30
More stable mood, energy, and recovery as consistent dosing locks in supported metabolic pathways.
Week
52
Long-term steadiness and capacity as ongoing mitochondrial and methylation support help cells handle stressors.
Year
1
Encourages the growth of fresh, more resilient mitochondria
Year
2
Encourages the growth of fresh, more resilient mitochondria
Weeks 1-4
Week 8
Week 16
Week 30
Week 52
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Day
1
Encourages the growth of fresh, more resilient mitochondria
Weeks
1-4
Early steadiness, subtle clarity, and less daily drag
Week
8
More reliable stamina andclear focus
Week
16
Faster recovery, clearer thinking, and greater resilience
Week
30
A more dependable baseline
Week
52
Long-term mitochondrial and cellular support that promotes healthy aging
Year
1
Encourages the growth of fresh, more resilient mitochondria
Year
2
Encourages the growth of fresh, more resilient mitochondria
Weeks 1-4
Week 8
Week 16
Week 30
Week 52
Weeks
1-4
Early steadiness, subtle clarity, and less daily drag
Week
8
More reliable stamina andclear focus
Week
16
Faster recovery, clearer thinking, and greater resilience
Week
30
A more dependable baseline
Week
52
Long-term mitochondrial and cellular support that promotes healthy aging
Year
1
Encourages the growth of fresh, more resilient mitochondria
Year
2
Encourages the growth of fresh, more resilient mitochondria
Benefits you'll feel
Weeks 1-4
Week 8
Week 16
Week 30
Week 52
Trusted by Practitioners
Trusted by Practitioners
Keshav K. Singh
PhD
Scientific Founder and Chief Scientific Officer, Yuva Biosciences, Inc.
"For almost 30 years, my work has centered on mitochondrial dysfunction as a driver of aging. Core100 applies a dual-action strategy, combining support for improving mitochondrial health with antioxidant defense."
Keshav K. Singh
PhD
Scientific Founder and Chief Scientific Officer, Yuva Biosciences, Inc.
"For almost 30 years, my work has centered on mitochondrial dysfunction as a driver of aging. Core100 applies a dual-action strategy, combining support for improving mitochondrial health with antioxidant defense."
See the benefits for yourself
Core100 is a mitochondrial protocol built on YuvaBio® Y100™, with targeted cofactors that support mitochondrial renewal and antioxidant defenses. Together, they help you maintain steadier daily energy and recovery.
See the benefits for yourself
CORE100 is a clinically considered daily protocol. It’s powered by our proprietary YuvaBio® Y100™, driving mitochondrial renewal, cellular repair, and decades-long resilience.
90-Day Baseline Promise
Run the full 90 days
If you don’t feel a meaningful shift in day-to-day steadiness by the end, we’ll make it right.
Transparent
Tested
Trusted
People usually ask about
How is Core100 different from a multivitamin or basic NAD+ booster?
A multivitamin is broad nutrient coverage. A basic NAD+ booster usually targets one pathway. Core100 is designed around five interconnected systems so you’re supporting the environment your mitochondria operate in - not just one lever.
Do I need to cycle Core100 or can I stay on it continuously?
You don’t need to “cycle” Core100 the way you might with stimulant-based products. Most people run it as a 90-day protocol, then continue taking it daily.
Can I take Core100 with my other supplements?
Often, yes. The main consideration is overlap - if you’re already taking separate NAD+ precursors, mitochondrial blends, CoQ10, or similar products, you may be doubling up.
Why choose Core100 instead of just a standard multivitamin?
A standard multivitamin covers broad micronutrient gaps but doesn’t specifically target how your cells make and manage energy. Core100 is built around mitochondrial and NAD+ systems, with ingredients and doses chosen for those functions rather than general coverage. Many people use both: a basic multivitamin as “background insurance” and Core100 as a focused energy and resilience protocol.
Do I need a subscription, or can I just do a single 90-day run?
You don’t need a subscription to use Core100. You can purchase it as a one-off 90-day protocol or as an ongoing subscription. A subscription simply makes it easier to stay consistent by ensuring your next bottle arrives before the current one runs out. You can usually pause, skip, or cancel from your account at any time; check the product page for the latest details.
People usually ask about
How is Core100 different from a multivitamin or basic NAD+ booster?
A multivitamin is broad nutrient coverage. A basic NAD+ booster usually targets one pathway. Core100 is designed around five interconnected systems so you’re supporting the environment your mitochondria operate in - not just one lever.
Do I need to cycle Core100 or can I stay on it continuously?
You don’t need to “cycle” Core100 the way you might with stimulant-based products. Most people run it as a 90-day protocol, then continue taking it daily.
Can I take Core100 with my other supplements?
Often, yes. The main consideration is overlap - if you’re already taking separate NAD+ precursors, mitochondrial blends, CoQ10, or similar products, you may be doubling up.
Why choose Core100 instead of just a standard multivitamin?
A standard multivitamin covers broad micronutrient gaps but doesn’t specifically target how your cells make and manage energy. Core100 is built around mitochondrial and NAD+ systems, with ingredients and doses chosen for those functions rather than general coverage. Many people use both: a basic multivitamin as “background insurance” and Core100 as a focused energy and resilience protocol.
Do I need a subscription, or can I just do a single 90-day run?
You don’t need a subscription to use Core100. You can purchase it as a one-off 90-day protocol or as an ongoing subscription. A subscription simply makes it easier to stay consistent by ensuring your next bottle arrives before the current one runs out. You can usually pause, skip, or cancel from your account at any time; check the product page for the latest details.